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   (Propolis) Ư() ̿()
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. (Propolis)
1. ΰ?
ִ ڪ̶ ִ. ܹ ڪκ () ڪ () ڪ̴.
ܹ() ڪ ̳ , ʵ ϱ ؼ Ǵ ڪ ߿ κ ϰ ڰڪ Ͽ ϴ ڪ Ƶ ̴.
ūλ() , Bacteria ж׾ ڪμ ϴ ܹ() ȿ Ͽ ִ ڪ ڪ ̴.(Lavie, 1978). 츮󿡼 ̸ () Ѵ.
ܹ() ̰ ޸ ؼ DZ ߶ ж׾ ̷(Virus) ϴµ Ѵ. , ҳ ߧհϱ ̸ ۮ Propolis (Coating)Ͽ ڰڪκ ϰ Ѵٴ ̴.(Lindenfesler, 1967).
̿ 򷸦 ڪ ڰڪ ϴ ڪ ֱ Ÿ ̴.(Swain, 1977).

2. (Propolis) Բ
.
츮 ʿ ĵǾ Դ. (ۮ: )̶  µ, ̴ (߾) پ ִ ũ () ϸ, 氣(: Ѩ ), (瘈瘲: ȴٸ ), (: Ѩ), (: ۮ Ѩ, , ۮ) ϴµ Ͽ. ׸, ˵Ϳ ۮ ᵷμ ̵ Ը, ߤ̶ ϰ ִ. δ ۮ ٷ() ,(), (ġ Ǽ ν) ߶() ľ ֶ Ͽ, Ρ, Ρ ߯ж ִٰ Ͽ. ̴ Ρʿ (Propolis) ̴.

.
Բ Ͽ, ܻ ϰ ϴµ ĵȴ. ݱ ĵȴ.
жİ ߫ ҵǰ , İ Ѧ ϴ ִ. ׸, Ȱ(߫) Ѵ. Ϲ ʥŰ ĵ ϴ.
⿡ ۯ , , ܻ , Ѣϰ ϼ ߿ ִ.
. ׾
ö󺸳̵(Flavonoid)μ ߫ϴ ˷ ִ.(Takahama , 1984). ߫ μ ߫ ִٰ ͱǾ, ö󺸳̵ ߫ Φ߫ ׷ ڪ Ͽ Ű ͱϿ.(Takahama , 1984)
۰ (1995) źÿ Ͽ  EEP(Ethanol Extracted Proplis) ʥϿ , ϴ ֺĮ(Potassium Sorbate) , EEP ۡϿ , Ѧ ߾ ũ .

. ʥڪ
(chewing gum), ĵ(candy) ˬ ʥ ǿ ǰ , ׸ Ѧ ĵǰ ִ.

. Ŀ
․(soap)․  ʥ ĵǰ ܬ ߧ Ѣ ũ.

3.
δ , װ(antimold), ж, ߫, ئ, ׹̷(antivirus), , ĵ , ο ִٴ ϼ̿ ݵǰ ִ.(Sakai , 1997).

. ж,
κ ء ĵǾ Դ. ܻ ĵ κ 2300Ҵ ׸(Greece) ܻ ͧ׾, ۰ (Hippocratic oath) ء ũ׽(Hipocrates: B.C460?-375?) ؼ̴. ״ ߿ ϴµ 獎ߴ. Greece ʫμ ڪ ۡ, ׾, , ϼ Ƹڷ(Aristotele:B.C.384-322) ݱܻ, Ѩ, ߿ Ͽٰ Ѵ. (boar war) ۸ (propolisin)̶ ڪ ° ݶ߿ ϴµ ĵǾ. Ǹ ۯ , , ߿, ˷ 뿡 ĵǰ ִ. (Atophy) ݱ ĵǾ.  ݱ, 縶, ߿ ݱ, 帧, ϼ , ִ ˷ ִ.(Lindenfelser, 1967).

. װ(anti mold), ж, ׹̷(antivirus)
׸ , ߯ж ԬϹж, ڶ, ͽж, ݯ蛆ܻж  ؼ propolis ϴ ũٰ Ѵ. ׸, ̷ ÷(Infruenza) A2  ؼ Ư, پ ߯ж Ÿ. , Գ, ҳ ۹ Ǵ Ʈڸ𳪵(Trichomonad) ̴ ٰ Ѵ. ׸, ڪ Ŀ ؼ ˭ȴٴ ͱ ִ.(Kivalkina and Bukarkova, 1978).
Ghisalberti(1979) ܹ ڪκ ڪ ж, , ئ ִٰ Ͽ, Matsuno(1992) propolis ж Ÿ Diterpene̶ ڪ Ͽ.

. Ȱ(߫) Ѧ
߫ȸ ϰ ̰ ĥ ߫ ݻ ߫(߫) ȴ. ̰ ߫ Ͽ ˭ ߫ ̿ Φ߫ڪ Ͽ 󱼿 ˹, , ָ , Ү ־ ̿ ߱ ִ ٤ ȴ. ߫ȸ Ǵ Ű ִ.(Scheller ,1988).
Pascual (1994) ΰ ׾ ٻ ΰ 뿡 ؼ ߫ȿ ؼ ȭ ۿ ٰ Ѵ. ϰ ö󺸳̵(Flavonoid) Φ߫, (Drogovoz , 1994), ߿ Ѧ ݥ, ж ִ .(,Takino Mochida, 1982). ׸, Φ߫ڪ ־ ۡ Ͽ Ѧ ߫ Ѧ Ͽ ־. (Chiao , 1995, 1992).

. ׾ۿ()
ϴµ Ѵٴ ͱ (Sakai, 1997). ̰ ִ Flavonoid:Ķ󺸳̵ δ. డ DZ ϴ . Scheller (1988) EEP ڪ鿡 ִٴ Ь٥Ͽ. Win Luchydenski ʹ Propolis ϰ 90% ߾ 5-10Ҵ ۡ ٰ ͱϿ ͣ ִ.
Matsuno(1992) Propolis ڪ ࿡ ߿ ִ ϰ Propolisκ ڪ ․Ͽ. ׸, ̰ ʥϿ ฦ ϸ 7 ں ߿ Ÿ Ͽ 2-3 డ ϴ ̸ۡϿ. ̿ ̿ ࿡ ̸ۡϿ, ࿡ ߿ ʴ Ÿ. ׸, Propolisκ CAPE(Caffeic acid phenethyl ester) ࿡ ؼ Ը Ÿ. ϸ (ǥ-1) .

<ǥ-1>


. (Propolis) ߧ
츮 ߧ ͪ ʾ, , , ߣ, , ̿,
211٣ 鿡 69% ߧϰ ְų ߧߴ ִ Ÿ. ε Өȴ.
ߧ 69% Ҵ 1 Ѵٰ , 21% Ҵ 2 Ѵٰ ߴ. , ߧʫ 90% Ҵ 1-2 ϴ .
δ ߧ 48% (mosquitonet) ߰, 27% ۼ(vinyl nets) ϰ , ݻ Hivetool ÷ ܾ ϴ Ÿ
211٣ 1995⿡ 335.5kg̾, 1996Ҵ 443.5kg 1997Ҵ 640kg, 1998Ҵ 783.5kg, ߧ ʥϴ ִ. , 1999Ҵ ߧ 973.5kg Ÿ. 1995Ҵ ߧ 100% 1996:132%,
1997:191%, 1998:234% ߧ Ÿ, 1999Ҵ 290% ߧ ҵȴ.

2. ߧʦ
ͪ Ǿ ʴ. ٸ, ϼ 1996Ҵ Ҵ 18ton ߧǴ ҵȴ.

<ǥ-2> ߧʦ


׷, 1996Ҵ μ ǰ ־, ߧ ʥϰ , ϼ̿ Ҵ 400g ߧ ִ Ͽ. Ү 40ؿؿ 400g߾ ߧѴٸ ߧ 160ton ̸. θ õǸ, 1kg ʤ̫ 7ؿ ߾ ̵ǹǷ ʫ 112 ߾ ʥ ø Өȴ. , ߧ 忡 ʫ 100 ߾ ̸ ߩ ִ
. ߧ
1. (׾)
ܹ ڪκ Ѵ. ׵ ϴ ˷ ׾ (a fir), ÷(poplar), ҳ(pine-tree), ĥ(maronnier), (Oak), ۳(Birch), 峪(Willow), 񳪹(Spruce), (Alder), ī(Eucarya) ִ. ܬ 캸, ڸп ī ǰ, ڸп ÷ ҳ ̷. ׸, Europe ַ ÷, ۳, , δϿ ׾ ⧿ Ѵ.(Ghisalberti, 1979). , Lavie(1978) ÷(poplar) ڪ Ѵٰ ִ.
츮󿡼 ܹ  ʿ ϴ ͧ ۰ ̷ ʾ, ϼ ̿, ַ ҳ(Pine), ÷(poplar), (Oak), ۳(Birch), (Elm) ʵκ ϴ .

2. ߧμ ÷(Poplar)
ߧ ؼ ҳ, ÷, ĥ, ҳ ÷ ´. Ư, ̸ () ÷(poplar) ɺ(ȭ: ) ΰ ִ () ִ ڪ () ϱ ϴ () Ķ󺸳̵(Flavonoid)׾ ڪ ߧμ Ѣȴ.
3. ÷(Poplar)
. Ǯ ߺ
ö , հ ũ Ǫ÷ 20cm © 30cm ΰ Ѵ. 15cm ϰ δ 1-2 ϸ ȴ.

. (ߺ) η
÷ ڶ ֵ Ư ö ۾ ú Ѵ. ϰ ġ 4-5cm ȭк 2-3g 2ȸ úѴ.

. ÷
÷ (ߺ)Ͽ Ҵ̸ 1-2m Ѵ. ̸ Ҵ Ͽ ܻѸ () 2° ڸ Ű ɴ .
1997 50 ߺ․ ̿, 21 Ͽ 42% Ÿ. 1998 110 ߺ ̿ 70 Ͽ 64% Ÿ г 53% Ÿ´.

. ߧ
1. ۼ 䰥ܬ ߧ
Ү ߧ Ǿ ,  ߧ ݵǾ ʴ. , ۡϴ ϴٴ Ө Ʒ, 1996, 1997, 1998 5 10 6 3Ҵ Ͽ. 츮󿡼 ϰ ִ ۼѰ ۼ ̰ Ͽ.
ᶷ (A) ۰ 30-40km ܫ4 (B,C,D,E) , ۼѿ ̿
ǥ-3 Ÿ 5 C 4忡 Ÿ, г 29g̻, 16% ߧ Ÿ. ٽøؼ ο ٴ ѿ Propolis Өȴ.

< ǥ-3 > ܬ, ܬ, Ҵ ߧ(1996)


ǥ-4 ۼ ߧ , 춰 ϱ Ͽ ʫ Propolis ϰ ִ Ķ Ȱ Ķ ۼ , ۼ ̿Ͽ 귮 Ͽ. ۼ ߧ Ƽ г 55.47g ߧǾ. 귮 Ķ μ г ߧ 50.27g̾. ̿ ۼ г ߧ 46.26g ҰϿ.
ͪ , ۼ ̰ ־, ˷ ϸ ۼѺ ۼ 9%, ۼ 19% ȴ.(ǥ-4).
ۼ ϴ ٶ Өȴ.

<ǥ-4> ۼ ܬ ߧ(g)


2. ܬ Propolisߧ
<ǥ-11> () ܬ (1999)

-1 ․․․ۼ Ӱ()Ѱ
-2 ․․․ ()

. ߧ
1.
ߧϱ ؼ ׾ ҳ(Pine-tree), ÷(Poplar) Ǿ ִ ؾ Ѵ. ׸, ܹ ׾ ڪ ڪ ܾ , ݵ Դ̳. ū Գظ  洿 ߧؾ Ѵ. Դ ڪ Գ ƽƮ Ƶ ˬ ׽Ű .
ؿö() ÿ(Ҳ) ߧ ڰϴ.

2. Ѣ
ۼ ϸ 4 ʦϴ. ׷. Ʈ(trap) ϸ īþƲ(honey of Acacia) ̿ Ƿ, īþƲ Ѵ. ϱ 9 ⿡ 10 ߧʦ ϴ.

3.
ۼ (٥) ۼ ؾ ߧ ϹǷ, (), , ۼ 2ݸ ޡ߾а Ѵ.
Trap 翡 Trap ޡ߾а ϰ (٥) ۼѰ ´.
ִ () Ǵ ۼ ´. ֿ  ֵ, Ѳ ణ ΰų  Ǹ Ͽ Үݻ , ׾ƹٸ ȴ.

4. η
ǵ ۼ̳ Trap Propolis ä Ǵ Ͽ ޡ߾а Ǿ äʴ ä쵵 . 3-4ο ä ۼ 2 ؿ ִ ͸ ޡ ߾а ٽ ۼ 2ݷ ִ ״ Ѵ. Trap 쵵 ۼ ϰ ηϳ, Trap Ƴ ۼѰ ִ ͩ Ѵ.
Ѩ Ү Ǵ η ۼ, Ʈ(Trap), ޡ߾а ǵ Ͽ Ѳ ݴ´.

5.
Ⱦ ۼѿ پ ִ ܹ , г(Wax), Ÿ ڪ Ѵ.
ޡ߾̳ κп پ ִ ̺(Hive tool) ܾ , ̳ Ʈ ĥ , ܹ ü Ÿ ڪ ʵ ؾ Ѵ. Ǵ ̿ ϴ 访 ݵ 尩 ϰ ϰ о, о ۼ ϵ Ѵ.

6. , ,
ݵ Ͽ ο ̳ õ £ ηѴ. ּ 10-15C Ѵ. Ѣ , Ѩ ޺() ʾƾ Ѵ.

. ۰
1. ܬ
ܬ, ܬ, ܬ ׸ η۰ ߧȴ. ܬϱ ؼ ü(޼Ҳ) ִ.
1 Ͽ 10 ޼⩿ 1 Ǵ 3ุ ȰͰ ʰ ϡϿ Ǵ ״ ڿ Ͽ Ѵ.

2. () ۰
ϱ ؼ ͳ ϡϴµ, ϴ (EEP : Ethanol extracted propolis) Ͽ Ѵ. ڿ ۰ ٸ.

. Ÿ(Ethanol)۰
1kg 90% Ÿ 2-3 Բ 6 ߾ Ϸ翡 2-3 Ͽ Ѵ.

. ()̳ () ϴ ۰
Ÿ 1kg () 90% 2-3Ϳ Ÿ ϰ Ѵ. () ݳ() Ƿ Ѣ (1Ҵ߾) 㰡 ʦ Ͽ ϴ .

. ϴ ۰
Ƿ 60 5-6 1kg Ͽ ȥձ(Mixer) 1 ڪ Ͽ ϴ ٶϴ.

3.
BC 2,300Ҵ ĵ (EUROPE) ˬ信 Ƽ, Լ£ ѿ , α ʫ ˬ ް ִٰ Ѵ.

. ּ Ķ󺸳̵(Flavonoid) ()
Ķ󺸳̵׾ ̸ ϰϴ 鿡 ȴ.

ʸ-(Artepillin C) - ļ(Macrophage)
()

缼ģ(Quercetin) -



īλ ĥ ׸(CAPE) - ุ ߿

. (ܻж) Propolis ΰ׻(ڪ)
ܻж ڪ ̿ ϽǸ, Ʈũ ׸ ̽ ٵ ׶缺Ϲж ؼ ߯ж پ ̿ Ÿ´. ̿ж ˭ ߯ж ־ ̿ Ͽ 먵 ͱ ҷ(SOVIET) ۡǰ ִ.
<ǥ-12> ܻж Propolis ڪ

(+)ణȿ (++)ȿ (+++) ȿ (-)ȿ

. Ϲ ʥ Ѧ
92 ᴿ ޸ ̰, Ѧ ִ 30 ()ѹ, 10 ǰ ִ Ϲ⦰ ǿ Ϲ⦵ þ 츮ġ ˬ .
׸ () 樸 ͩϴ 鿡 Ϲ⦰ 2,000-3,000/ , 30 Ա ķδ 𥸦 ߾ Ϲ⦰ ʥϿ 5,500/ ߾㰽 Ӹ ƴ϶ ˭Ǿ.

. ฦ ϴ NK(Natural Killer) ʥ
NK () Ϲ 3-8% ϸ, Killer Ÿ Ѧ ִ. ࿡ ʰ ̷(Virus) ೪ Killer Ȱ() Ÿ. NK ࿡ ؼ վ Ψأ Ѵ. ¿ ࿡ հ Ÿ. ׷ NK ־ Ǵ ִ. 4 3  ڪ 30ml ̿ () NKcell 1 ݥ, ͩ ʥ Ÿ ִ. ׸ NKడ () 2 ̿ 13%-19% ʥϿ г 17% ʥ ̿ ͱǰ ִ.

. B м
() м Ÿ μ 55 B , Կ GPT () 2,000 Ѿ ӭѢ࿡ Ȱ ˬ ݥߴ. C ط 56 ̿ ܳ ִٴ Ө , Ϲ ʦ ѹ, Ҵ⸸ Ѧ ༵ǰ ˬ ݥߴ.

. ()
⿡ (٤), 1-6 ͱ ް 20-30ml ̿ Ǿ ޿ ϰ ִٴ ۡǰ ִ. 䫴 40٣ 35٣ , 5٣ 칵 ᳵǰ ʥϿ () Ǿٰ ۡϰ ִ.

. (Propolis) () ۰
ƹԳ ñ ϰ ִ ִ. ˬ ˬ ؼ ׸ ܻ 머 ؼ ϰ ȴ. ǵ̸ Ʒ Ͽ Ͽ߸ ִٰ ȴ.

1. ⩺ٴ ⩿ Propolis ()Ͽ ô() ̴.

2. ñ ۰ Ŵ.
ز ̳, ⩿ Բ Ÿ ϴ Ƿ( ), Ѿ()ó ګ ״ ϴ ̴.

3.  ־ () 翡 巰 Բ 2-3 ̰ ΰ ϴ ̴.

4. () (ػ) ٴ ̳ ()ÿ ϴ ̴.

5. Ͽ () 1 3޿ ļ ϴ ͺٴ () ͩ ü() ֵ ϴ() ̴ٰ ȴ.
߱ ǷẸǿ 迬
Ư()
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